You have found the work-related webpages of Alex Buerkle. I am a geneticist, computational biologist, and evolutionary biologist. I was previously a professor at the University of Wyoming (2004 to 2022). Then I worked as a senior data scientist at Gencove (through 2023) on applications of low-depth DNA sequencing in human and agricultural genomics. Most recently, I worked as a Staff Bioinformatics Scientist at Illumina (through June 2026), developing computational methods for clinical genomics, including methods for detecting circulating tumor DNA and copy number variants. Now I am doing science as a professor emeritus at the University of Wyoming, based in beautiful Laramie, Wyoming.
Blog
I post short articles on my Laramide Intelligence blog, mostly regarding machine and statistical learning.
Buerkle lab
The Buerkle lab concluded its operations in May of 2022. Research in our group focused on evolutionary and ecological genomics and computational biology. You might be interested in members of our lab.
Software
- entropy — Model-based genotype and ancestry estimation
- CNVRG — R package that provides a wrapper and STAN code for Dirichlet-multinomial modeling of count data
- hindex — software for estimation of a hybrid index
- introgress — software for mapping components of isolation in hybrids
- bamova — software that implements a Bayesian Analysis of Molecular Variance
- bgc — software that implements Bayesian estimation of genomic clines
- dfuse and simadmix — programs for forward-in-time simulation of hybridization and admixture
